Sören Krach

Distinct Volume Alterations of Thalamic Nuclei Across the Schizophrenia Spectrum

Distinct Volume Alterations of Thalamic Nuclei Across the Schizophrenia Spectrum Melissa Thalhammer, … Stefan Borgwardt, … Mihai Avram,…  DOI: doi.org/10.1093/schbul/sbae037 Abstract Background and Hypothesis Abnormal thalamic nuclei volumes and their link to cognitive impairments have been observed in schizophrenia. However, whether and how this finding extends to the schizophrenia spectrum is unknown. We hypothesized a distinct …

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Towards a Better understanding of Persisting Perceptual Disturbances following the use of Classic Psychedelics.

Für ein besseres Verständnis anhaltender Wahrnehmungsstörungen nach der Einnahme klassischer Psychedelika Towards a Better understanding of Persisting Perceptual Disturbances following the use of Classic Psychedelics. Mihai Avram, …, Stefan Borgwardt, …    DOI: doi.org/10.1055/a-2264-6472 Klassische Psychedelika wie Psilocybin, Lysergsäurediethylamid (LSD), Ayahuasca oder 5-Methoxy-Dimethyltryptamin (5-MeO-DMT) stehen wieder vermehrt im Fokus des psychiatrisch-psychotherapeutischen und neurowissenschaftlichen Interesses. Dies …

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Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system – a retrospective cohort study

Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system – a retrospective cohort study Katharina Wien, …, Stefan Borgwardt DOI: doi.org/10.3389/fpsyt.2024.1304844 Abstract Introduction: In 2021, a computerized physician order entry (CPOE) system with an integrated clinical decision support system (CDSS) was implemented at a tertiary care …

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Journal of nephrology

Clinical and histopathological characteristics of acute kidney injury in a cohort of brain death donors with procurement biopsies

Clinical and histopathological characteristics of acute kidney injury in a cohort of brain death donors with procurement biopsies Florian G. Scurt, …, Alexandra Korda, … DOI: https://doi.org/10.1007/s40620-024-01940-9 Abstract Background Kidney biopsies are routinely used for diagnostic and prognostic purposes but their utility in the intensive care unit (ICU) setting is limited. We investigated the associations …

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Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders

Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders Linnea Hoheisel, … Stefan Borgwardt, … PRONIA Consortium   DOI: 10.1016/j.bpsc.2024.02.013 Abstract Background Psychosis and depression patients exhibit widespread neurobiological abnormalities. The analysis of dynamic functional connectivity (dFC), allows for the detection of changes in complex brain activity patterns, providing insights into common and unique processes underlying these …

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Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning

  Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning Else Schneider, … Stefan Borgwardt, …  DOI: 10.3389/fnagi.2024.1357695 Summary Associative memory is arguably the most basic memory function and therein constitutes the foundation of all episodic and semantic memory processes. At the same time, the decline of associative memory represents …

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Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation

Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation Ruiyang Ge, … Stefan Borgwardt, …   DOI: 10.1016/S2589-7500(23)00250-9 Summary The value of normative models in research and clinical practice relies on their robustness and a systematic comparison of different modelling algorithms and parameters; however, this has not been done to …

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Altered Perception of Environmental Volatility During Social Learning in Emerging Psychosis

Altered Perception of Environmental Volatility During Social Learning in Emerging Psychosis Daniel J. Hauke, … Christina Andreou, … Stefan Borgwardt, …  DOI: 10.5334/cpsy.95 Abstract Paranoid delusions or unfounded beliefs that others intend to deliberately cause harm are a frequent and burdensome symptom in early psychosis, but their emergence and consolidation still remains opaque. Recent theories …

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Management of treatment resistance-Treatment-resistant schizophrenia

Management of treatment resistance-Treatment-resistant schizophrenia Elias Wagner, Stefan Borgwardt & Alkomiet Hasan      DOI: 10.1007/s00115-024-01608-6 Abstract Despite a very high prevalence and substantial impairments among affected individuals, treatment-resistant schizophrenia (TRS) has not been sufficiently researched in clinical research in the field of psychiatric disorders and the pathophysiology is still poorly understood. A better clinical and pathophysiological …

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