Sören Krach

Neural Dynamics of Social Cognition: A Single-Trial Computational Analysis of Learning Under Uncertainty

Neural Dynamics of Social Cognition: A Single-TrialComputational Analysis of Learning Under Uncertainty Colleen E Charlton, Daniel J Hauke, … ,  Stefan Borgwardt, …  DOI: 10.1002/hbm.70433 Abstract Understanding others’ intentions amidst uncertainty is critical for effective social interactions, yet the neural mechanisms under-lying this process are not fully understood. Here, we combined computational modeling and single-trial […]

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The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis

The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis Frederike Schröpfer, Emilia Greif, Sofia Eickhoff, … , Stefan Borgwardt & Léon Franzen  DOI: 10.1007/s00787-025-02937-w Abstract Mental disorders represent a significant challenge for individuals and society. Many of them have

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Perspectives of mothers and fathers affected by addiction of an adolescent/adult child – results from a mixed-method study

Perspectives of mothers and fathers affected by addiction of an adolescent/adult child – results from a mixed-method study Anja Bischof, Richard Velleman, Stefan Borgwardt, Hans-Juergen Rumpf & Gallus Bischof DOI: 10.1186/s13690-025-01826-7 Abstract Background Addiction has an impact not only on the individual but also on family members. Stress and strain are high especially in parents

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Mapping symptom dimensions in early psychosis through neurotransmitter-informed co-localization of structural and functional brain alterations

Mapping symptom dimensions in early psychosis through neurotransmitter-informed co-localization of structural and functional brain alterations L. Hahn, M. Sacha, … , S Borgwardt, …  DOI: 10.1016/j.nsa.2025.106605 Abstract Traditional diagnostic tools like the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) and the Scale for the Assessment of Negative Symptoms (SANS) assess broad symptom domains but

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Mental health, coping and related risk factors during the first 2 years of the COVID-19 pandemic in children: Nationally representative, multi-wave, cross-sectional results from 12 countries from the global COH-FIT study

Mental health, coping and related risk factors during the first 2 years of the COVID-19 pandemic in children: Nationally representative, multi-wave, cross-sectional results from 12 countries from the global COH-FIT study Agorastos Agorastos, Trevor Thompson, … , Stefan Borgwardt, … DOI: 10.1016/j.euroneuro.2025.112741 Abstract Few multinational studies have assessed risk factors and coping strategies associated with

Mental health, coping and related risk factors during the first 2 years of the COVID-19 pandemic in children: Nationally representative, multi-wave, cross-sectional results from 12 countries from the global COH-FIT study Read More »

Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis

Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis David Popovic, … , Stefan Borgwardt, Stephen J Wood, Eva Meisenzahl, Nikolaos Koutsouleris, Rachel Upthegrove, PRONIA Consortium  DOI: 10.1001/jamapsychiatry.2025.3803 Abstract Importance  Inflammation is increasingly implicated in the pathophysiology of mood and psychotic disorders. Integrating blood biomarkers and brain imaging may help uncover mechanistic pathways and guide targeted interventions.

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Prof. Borgwardt continues to be a leading figure in Psychiatry as Highly Cited Researcher in 2025

We congratulate Professor Stefan Borgwardt on being named a Clarivate Highly Cited Researcher for the eigth year in a row. This renewed selection is a tremendous achievement and underlines the importance of his scientific work and the high standing of his Translational Psychiatry lab in the field. This award comes at no surprise, as his

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Structural covariance network topology in individuals at clinical high risk for psychosis: the ENIGMA-CHR Study

Structural covariance network topology in individuals at clinical high risk for psychosis: the ENIGMA-CHR Study Siwei Liu, Ingrid Agartz, Paul Allen, G Paul Amminger, Ole A Andreassen, Peter Bachman, Inmaculada Baeza, Helen Baldwin, Cali F Bartholomeusz, Stefan Borgwardt, …  DOI: 10.1038/s41380-025-03304-6 Abstract Brain network architecture is anticipated to influence future grey matter loss in individuals

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From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Madalina-Octavia Buciuman, Shalaila S Haas, … , Stefan Borgwardt, Dominic B Dwyer, Lana Kambeitz-Ilankovic, Nikolaos Koutsouleris DOI:  10.1016/j.biopsych.2025.07.003 Abstract Background Early recovery of functioning is critical for favorable outcomes in psychotic and affective disorders.

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Read More »

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression Svenja Sürig, … ,  Stefan Borgwardt, Jan Philipp Klein, Thomas Probst DOI: 10.1080/16506073.2025.2464641   Abstract While most psychotherapy methods are about equally effective, it is unclear if (1) different methods of psychotherapy differ

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