Sören Krach

Structural covariance network topology in individuals at clinical high risk for psychosis: the ENIGMA-CHR Study

Structural covariance network topology in individuals at clinical high risk for psychosis: the ENIGMA-CHR Study Siwei Liu, Ingrid Agartz, Paul Allen, G Paul Amminger, Ole A Andreassen, Peter Bachman, Inmaculada Baeza, Helen Baldwin, Cali F Bartholomeusz, Stefan Borgwardt, …  DOI: 10.1038/s41380-025-03304-6 Abstract Brain network architecture is anticipated to influence future grey matter loss in individuals […]

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From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Madalina-Octavia Buciuman, Shalaila S Haas, … , Stefan Borgwardt, Dominic B Dwyer, Lana Kambeitz-Ilankovic, Nikolaos Koutsouleris DOI:  10.1016/j.biopsych.2025.07.003 Abstract Background Early recovery of functioning is critical for favorable outcomes in psychotic and affective disorders.

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Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression Svenja Sürig, … ,  Stefan Borgwardt, Jan Philipp Klein, Thomas Probst DOI: 10.1080/16506073.2025.2464641   Abstract While most psychotherapy methods are about equally effective, it is unclear if (1) different methods of psychotherapy differ

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Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia

Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia Zoey Stark, Karine Elalouf, Vanessa Soldano, Léon Franzen & Aaron P. Johnson DOI: 10.1002/dys.1797   Abstract Dyslexia is a language-based neurobiological and developmental learning disability marked by inaccurate and disfluent word recognition, poor decoding, and difficulty spelling. Individuals can be diagnosed with and

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Open Science Award 2024 for Dr. Léon Franzen

  Open Science Award 2024 This year’s open science award of the Univeristy of Lübeck goes to Dr. Léon Franzen for his project on a best practice guideline for running behavioural studies in neuroscience and psychology successfully online. The Translational Psychiatry Lab congratulates him on this fantastic achievement, which showcases the interdisciplinary approach and team

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Dyslexia can make you richer (@Nights of open Knowledge; Nook 2024)

Dyslexia can make you richer – and the debunking of dyslexia myths Léon Franzen Public engagement talk (open to everyone in Lübeck) Dr. Léon Franzen will be part of this year’s Nights of open Knowledge, hosted by the University of Lübeck on November 8th and 9th. The organisers have put together a fantastic programme including

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Individualized pretest risk estimates to guide treatment decisions in patients with clinical high risk for psychotic disorders

Individualized pretest risk estimates to guide treatment decisions inpatients with clinical high risk for psychotic disorders Elodie Sprüngli-Toffel,  … , Stefan Borgwardt, Christina Andreou DOI: 10.1016/j.sjpmh.2024.09.001   Abstract Introduction: Clinical high risk for psychosis (CHR) states are associated with an increased risk of transition to psychosis. However, the predictive value of CHR screening interviews is

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Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine

Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine Mihai Avram, …, Alexandra Korda, …, Helena Rogg, …, Stefan Borgwardt  DOI: 10.1038/s41380-024-02734-y   Abstract Psychedelics have recently attracted significant attention for their potential to mitigate symptoms associated with various psychiatric disorders. However, the precise neurobiological mechanisms responsible for these effects

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