Sören Krach

Pattern classification as decision support tool in antipsychotic treatment algorithms

Pattern classification as decision support tool in antipsychotic treatment algorithms Alexandra I Korda 1, Christina Andreou 1, Stefan Borgwardt 2   Abstract Pattern classification aims to establish a new approach in personalized treatment. The scope is to tailor treatment on individual characteristics during all phases of care including prevention, diagnosis, treatment, and clinical outcome. In psychotic disorders, this need results …

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Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression

  JAMA Psychiatry Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression   Nikolaos Koutsouleris123, Dominic B Dwyer1, Franziska Degenhardt45, Carlo Maj6, Maria Fernanda Urquijo-Castro1, Rachele Sanfelici17, David Popovic18, Oemer Oeztuerk18, Shalaila S Haas9, Johanna Weiske1, Anne Ruef1, Lana Kambeitz-Ilankovic10, Linda A Antonucci11, Susanne Neufang12, Christian Schmidt-Kraepelin12, Stephan Ruhrmann10, Nora Penzel10, Joseph Kambeitz10, Theresa K Haidl10, Marlene Rosen10, Katharine Chisholm13, Anita Riecher-Rössler14, Laura Egloff14, André Schmidt14, Christina Andreou14, Jarmo Hietala15, Timo Schirmer16, Georg Romer17, Petra …

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CBBM-Lecture by Gerhard Jocham

Our collaborator in the Psychology department, the Obleser-group, featured a CBBM-lecture by Prof. Gerhard Jocham (Biological Psychology of Decision Making Institute of Experimental Psychology, HHU Düsseldorf). Title: Decision making: memory, patch-leaving and cortical mechanisms Abstract: The first part of the presentation will focus on the bi-directional interaction between memory and decision making. Decisions are guided by information stored in memory. I will …

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The Psychopathology and Neuroanatomical Markers of Depression in Early Psychosis

The Psychopathology and Neuroanatomical Markers of Depression in Early Psychosis  Rachel Upthegrove, Paris Lalousis, Pavan Mallikarjun, Katharine Chisholm, Sian Lowri Griffiths, Mariam Iqbal, Mirabel Pelton, Renate Reniers, Alexandra Stainton, Marlene Rosen, Anne Ruef, Dominic B Dwyer, Marian Surman, Theresa Haidl, Nora Penzel, Lana Kambeitz-llankovic, Alessandro Bertolino, Paolo Brambilla, Stefan Borgwardt, Joseph Kambeitz, Rebekka Lencer, Christos Pantelis, Stephan Ruhrmann, Frauke Schultze-Lutter, Raimo K R Salokangas, Eva Meisenzahl, Stephen J Wood, Nikolaos Koutsouleris, PRONIA Consortium   Schizophrenia Bulletin, Volume 47, Issue 1, January 2021, …

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General psychopathology links burden of recent life events and psychotic symptoms in a network approach

General psychopathology links burden of recent life events and psychotic symptoms in a network approach Linda T. Betz, Nora Penzel, Lana Kambeitz-Ilankovic, Marlene Rosen, Katharine Chisholm, Alexandra Stainton, Theresa K. Haidl, Julian Wenzel, Alessandro Bertolino, Stefan Borgwardt, Paolo Brambilla, Rebekka Lencer, Eva Meisenzahl, Stephan Ruhrmann, Raimo K. R. Salokangas, Frauke Schultze-Lutter, Stephen J. Wood, Rachel Upthegrove, Nikolaos Koutsouleris, Joseph Kambeitz & the PRONIA consortium npj …

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Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes

Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes David Popovic, Anne Ruef, Dominic B. Dwyer, Linda A. Antonucci, Julia Eder, Rachele Sanfelici, Lana Kambeitz-Ilankovic, Omer Faruk Oztuerk, Mark S. Dong, Riya Paul, Marco Paolini, Dennis Hedderich, Theresa Haidl, Joseph Kambeitz, Stephan Ruhrmann, Katharine Chisholm, Frauke Schultze-Lutter, Peter Falkai, Giulio PergolaGiuseppe …

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Selective suppression of rapid eye movement sleep increases next-day negative affect and amygdala responses to social exclusion

Selective suppression of rapid eye movement sleep increases next-day negative affect and amygdala responses to social exclusion Robert W. Glosemeyer, Susanne Diekelmann, Werner Cassel, Karl Kesper, Ulrich Koehler, Stefan Westermann, Armin Steffen, Stefan Borgwardt, Ines Wilhelm, Laura Müller-Pinzler, Frieder M. Paulus, Sören Krach & David S. Stolz  Scientific Reports volume 10, Article number: 17325 (2020) Published: 14 October 2020

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