Sören Krach

Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system – a retrospective cohort study Katharina Wien, …, Stefan Borgwardt DOI: doi.org/10.3389/fpsyt.2024.1304844 Abstract Introduction: In 2021, a computerized physician order entry (CPOE) system with an integrated clinical decision support system (CDSS) was implemented at a tertiary care […]

Clinical and histopathological characteristics of acute kidney injury in a cohort of brain death donors with procurement biopsies Florian G. Scurt, …, Alexandra Korda, … DOI: https://doi.org/10.1007/s40620-024-01940-9 Abstract Background Kidney biopsies are routinely used for diagnostic and prognostic purposes but their utility in the intensive care unit (ICU) setting is limited. We investigated the associations

Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders Linnea Hoheisel, … Stefan Borgwardt, … PRONIA Consortium   DOI: 10.1016/j.bpsc.2024.02.013 Abstract Background Psychosis and depression patients exhibit widespread neurobiological abnormalities. The analysis of dynamic functional connectivity (dFC), allows for the detection of changes in complex brain activity patterns, providing insights into common and unique processes underlying these

  Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning Else Schneider, … Stefan Borgwardt, …  DOI: 10.3389/fnagi.2024.1357695 Summary Associative memory is arguably the most basic memory function and therein constitutes the foundation of all episodic and semantic memory processes. At the same time, the decline of associative memory represents

Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation Ruiyang Ge, … Stefan Borgwardt, …   DOI: 10.1016/S2589-7500(23)00250-9 Summary The value of normative models in research and clinical practice relies on their robustness and a systematic comparison of different modelling algorithms and parameters; however, this has not been done to

Altered Perception of Environmental Volatility During Social Learning in Emerging Psychosis Daniel J. Hauke, … Christina Andreou, … Stefan Borgwardt, …  DOI: 10.5334/cpsy.95 Abstract Paranoid delusions or unfounded beliefs that others intend to deliberately cause harm are a frequent and burdensome symptom in early psychosis, but their emergence and consolidation still remains opaque. Recent theories

Management of treatment resistance-Treatment-resistant schizophrenia Elias Wagner, Stefan Borgwardt & Alkomiet Hasan      DOI: 10.1007/s00115-024-01608-6 Abstract Despite a very high prevalence and substantial impairments among affected individuals, treatment-resistant schizophrenia (TRS) has not been sufficiently researched in clinical research in the field of psychiatric disorders and the pathophysiology is still poorly understood. A better clinical and pathophysiological

In a recent radio interview with the Offener Kanal Lübeck (Open Channel Lübeck) Marco Heide, the medical head of our Baltic Early Treatment Service (BEATS), elaborated on the service’s help for young people and adolescents experiencing symptoms of psychosis. He highlighted the wide-ranging support this service in Lübeck offers to help-seeking adolescents and adults aged 15-35.

Brain texture as a marker of transdiagnostic clinical profiles in patients with recent-onset psychosis and depression Alexandra Korda, Christina Andreou … Stefan Borgwardt & the PRONIA Consortium  DOI: 10.1038/s44220-023-00168-z Abstract The inter-relationships of voxels can be captured by the radiomics texture features across multiple spatial scales. Prediction models of brain texture changes captured by the