Publications

The serotonin hypothesis in depression – interview with Prof. Borgwardt

A recent article in The Zeit explores the evidence for the serotonin hypothesis of depression including an interview with Stefan Borgwardt. Specifically, it critically examines the evidence provided by a recent overview article questioning serotonin as a crucial neurotransmitter in the etiology of depression. However, as professor Borgwardt stated, for complex disorders such as depression, …

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The non-specific nature of mental health and structural brain outcomes following childhood trauma

The non-specific nature of mental health and structural brain outcomes following childhood trauma Theresa K Haidl, …. Stefan Borgwardt  2023, Psychol Med DOI: 10.1017/S0033291721002439 Abstract Background: Childhood trauma (CT) is associated with an increased risk of mental health disorders; however, it is unknown whether this represents a diagnosis-specific risk factor for specific psychopathology mediated by …

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Chaos analysis of the cortical boundary for the recognition of psychosis

Chaos analysis of the cortical boundary for the recognition of psychosis Alexandra I. Korda, Christina Andreou, Mihai Avram, Marina Frisman, …, Stefan Borgwardt  2023, J Psychiatry Neurosci DOI: https://doi.org/10.1503/jpn.220160 Abstract Background: Structural MRI studies in people with first-episode psychosis (FEP) and those in the clinical high-risk (CHR) state have consistently shown volumetric abnormalities that depict …

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Circadian rhythms in auditory hallucinations and psychosis.

Circadian rhythms in auditory hallucinations and psychosis Hong-Viet V Ngo, … Christina Andreou, …  2023, Acta Physiol DOI: 10.1111/apha.13944 Abstract Circadian rhythms are imprinted in all organisms and influence virtually all aspects of physiology and behavior in adaptation to the 24-h day-night cycle. This recognition of a circadian timekeeping system permeating essentially all healthy functioning …

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Effects of a probiotic add-on treatment on fronto-limbic brain structure, function, and perfusion in depression: Secondary neuroimaging findings of a randomized controlled trial

Effects of a probiotic add-on treatment on fronto-limbic brain structure, function, and perfusion in depression: Secondary neuroimaging findings of a randomized controlled trial  Gulnara Yamanbaeva, … Stefan Borgwardt, ….  2023, Journal of Affective Disorders DOI: 10.1016/j.jad.2022.12.142 Abstract Background: Probiotics are suggested to improve depressive symptoms via the microbiota-gut-brain axis. We have recently shown a beneficial clinical …

Effects of a probiotic add-on treatment on fronto-limbic brain structure, function, and perfusion in depression: Secondary neuroimaging findings of a randomized controlled trial Read More »

Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trial

Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trial  Yu-Shiuan Lin, … Stefan Borgwardt, ….  2023, Scientific Reports DOI: 10.1038/s41598-022-26808-5 Abstract Acute caffeine intake has been found to increase working memory (WM)-related brain activity in healthy adults without improving behavioral performances. The impact of daily …

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Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial  Else Schneider, … Stefan Borgwardt, ….  2023, Journal of Psychiatry and Neuroscience DOI: 10.1503/jpn.220117 Abstract In major depressive disorder (MDD), cognitive dysfunctions strongly contribute to functional impairments but are barely …

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial Read More »

How to Run Behavioural Experiments Online: Best Practice Suggestions for Cognitive Psychology and Neuroscience

How to Run Behavioural Experiments Online: Best Practice Suggestions for Cognitive Psychology and Neuroscience Nathan Gagné and Léon Franzen  2023, Swiss Psychology Open: The Official Journal of the Swiss Psychological Society DOI: 10.5334/spo.34 Abstract The combination of a replication crisis, the global COVID-19 pandemic in 2020, and recent technological advances, have accelerated the on-going transition …

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