Publications

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Madalina-Octavia Buciuman, Shalaila S Haas, … , Stefan Borgwardt, Dominic B Dwyer, Lana Kambeitz-Ilankovic, Nikolaos Koutsouleris DOI:  10.1016/j.biopsych.2025.07.003 Abstract Background Early recovery of functioning is critical for favorable outcomes in psychotic and affective disorders. […]

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Read More »

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression Svenja Sürig, … ,  Stefan Borgwardt, Jan Philipp Klein, Thomas Probst DOI: 10.1080/16506073.2025.2464641   Abstract While most psychotherapy methods are about equally effective, it is unclear if (1) different methods of psychotherapy differ

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression Read More »

Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia

Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia Zoey Stark, Karine Elalouf, Vanessa Soldano, Léon Franzen & Aaron P. Johnson DOI: 10.1002/dys.1797   Abstract Dyslexia is a language-based neurobiological and developmental learning disability marked by inaccurate and disfluent word recognition, poor decoding, and difficulty spelling. Individuals can be diagnosed with and

Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia Read More »

Individualized pretest risk estimates to guide treatment decisions in patients with clinical high risk for psychotic disorders

Individualized pretest risk estimates to guide treatment decisions inpatients with clinical high risk for psychotic disorders Elodie Sprüngli-Toffel,  … , Stefan Borgwardt, Christina Andreou DOI: 10.1016/j.sjpmh.2024.09.001   Abstract Introduction: Clinical high risk for psychosis (CHR) states are associated with an increased risk of transition to psychosis. However, the predictive value of CHR screening interviews is

Individualized pretest risk estimates to guide treatment decisions in patients with clinical high risk for psychotic disorders Read More »

Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine

Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine Mihai Avram, …, Alexandra Korda, …, Helena Rogg, …, Stefan Borgwardt  DOI: 10.1038/s41380-024-02734-y   Abstract Psychedelics have recently attracted significant attention for their potential to mitigate symptoms associated with various psychiatric disorders. However, the precise neurobiological mechanisms responsible for these effects

Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine Read More »

Serum Metabolites as Potential Markers and Predictors of Depression-like Behavior and Effective Fluoxetine Treatment in Chronically Socially Isolated Rats

Serum Metabolites as Potential Markers and Predictors of Depression-like Behavior and Effective Fluoxetine Treatment in Chronically Socially Isolated Rats Dragana Filipović, … , Alexandra Korda, … , Stefan Borgwardt DOI: 10.3390/metabo14080405   Abstract Metabolic perturbation has been associated with depression. An untargeted metabolomics approach using liquid chromatography-high resolution mass spectrometry was employed to detect and

Serum Metabolites as Potential Markers and Predictors of Depression-like Behavior and Effective Fluoxetine Treatment in Chronically Socially Isolated Rats Read More »

We like to move it – patients with schizophrenia spectrum disorders are impaired in estimating their physical fitness levels and benefit from individualized exercise

We like to move it – patients with schizophrenia spectrum disorders are impaired in estimating their physical fitness levels and benefit from individualized exercise Wido Rippe, … , Stefan Borgwardt, … DOI: 10.1007/s00406-024-01844-6   Abstract Background: People with schizophrenia spectrum disorders (SSD) engage less in physical activity than healthy individuals. The impact of subjectively assessed physical fitness

We like to move it – patients with schizophrenia spectrum disorders are impaired in estimating their physical fitness levels and benefit from individualized exercise Read More »

Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis

Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis Eamonn Kennedy, …, Mihai Avram, …, Stefan Borgwardt, … DOI: 10.3390/brainsci14070669 Abstract Deficits in memory performance have been linked to a wide range of neurological andneuropsychiatric conditions. While many studies have assessed the memory impacts of individ-ual conditions, this study

Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis Read More »

Which Are the Optimal Screening Tools for Internet Use Disorder in Children and Adolescents? A Systematic Review of Psychometric Evidence

Which Are the Optimal Screening Tools for Internet Use Disorderin Children and Adolescents? A Systematic Review of PsychometricEvidence Samantha Schlossarek, …, Stefan Borgwardt, … DOI: 10.1007/s40429-024-00568-w Abstract Purpose of Review The early detection of problematic Internet use (PIU) is essential to prevent the development of Internetuse disorders (IUD). Although a variety of screening tools have already

Which Are the Optimal Screening Tools for Internet Use Disorder in Children and Adolescents? A Systematic Review of Psychometric Evidence Read More »

Neurobiologie und Wirkmodelle zu Psychedelika

Neurobiologie und Wirkmodelle zu Psychedelika Neurobiology and modes of action of psychedelics Uwe Herwig, Mihai Avram, Stefan Borgwardt, … DOI: 10.1055/a-2261-0745 Zusammenfassung Zur Beantwortung der Frage, ob Psychedelika eine therapeutische Wirkung bei psychischen Erkrankungen aufweisen, ist entscheidend, sich mit möglichen Wirkmechanismen auseinanderzusetzen. Solche können auf psychopharmakologischer, neurobiologischer, neurosystemischer und psychotherapeutischer Ebene beschrieben werden. Neben der klassischen

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