Publications

Motivational brief interventions for adolescents and young adults with Internet use disorders: A randomized-controlled trial Hannah Schmidt, … Stefan Borgwardt  2022, Journal of Behavioral Addictions DOI: 10.1556/2006.2022.00049 Abstract Adolescents and young adults (AYA) have an increased risk for Internet use disorders (IUD) compared to older individuals that may lead to functional impairments in daily life. To date, …

Motivational brief interventions for adolescents and young adults with Internet use disorders: A randomized-controlled trial Read More »

Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes Paris Alexandros Lalousis, … Christina Andreou  2022, Biological Psychiatry DOI: doi.org/10.1016/j.biopsych.2022.03.021 Abstract Identifying neurobiologically based transdiagnostic categories of depression and psychosis may elucidate heterogeneity and provide better candidates for predictive modeling. We aimed to identify clusters across patients with recent-onset depression (ROD) and recent-onset psychosis …

Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes Read More »

Influence of chronotype on the incidence and severity of perinatal depression in the “Life-ON” study Corrado Garbazza, …. Stefan Borgwardt,… 2022, Journal of Affective Disorders DOI: 10.1016/j.jad.2022.08.064 Abstract Perinatal depression (PND) is a severe complication of pregnancy, but there are no established risk factors predicting the disease. Evening chronotype has been associated with unhealthy lifestyle habits and …

Influence of chronotype on the incidence and severity of perinatal depression in the “Life-ON” study Read More »

The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis Johanna M Schwarzer … Alexandra Korda … Stefan Borgwardt  2022, Neuropsychopharmacology DOI: 10.1038/s41386-022-01385-3 Abstract Subtle subjective visual dysfunctions (VisDys) are reported by about 50% of patients with schizophrenia and are suggested to predict psychosis states. Deeper insight into VisDys, particularly in early …

The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis Read More »

Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited Nikolaos Koutsouleris, … Stefan Borgwardt, ….  DOI: 10.1001/jamapsychiatry.2022.2075 Abstract The behavioral and cognitive symptoms of severe psychotic disorders overlap with those seen in dementia. However, shared brain alterations remain disputed, and their relevance for patients in at-risk disease stages has not been …

Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited Read More »

  Special Collection on  “Hallucinations and Delusions” – call for submissions   Hallucination is understood as the perception of something that is not there and delusion as the belief of something despite contrary evidence. Both are commonly associated with psychiatric conditions such as schizophrenia, Alzheimer’s disease, or bipolar disorder. However, they sometimes also manifest in …

Special Collection “Hallucinations and Delusions” – call for submissions Read More »

Think-aloud analysis of commonly used screening instruments for Internet use disorders: The CIUS, the IGDT-10, and the BSMAS Hannah Schmidt, … Stefan Borgwardt, ….  DOI: 10.1556/2006.2022.00034 Abstract Despite the constant publication of new screening instruments for Internet use disorders (IUD), little is known about their content validity. This study aimed to identify potential mismatches between the …

Think-aloud analysis of commonly used screening instruments for Internet use disorders: The CIUS, the IGDT-10, and the BSMAS Read More »

Pattern of predictive features of continued cannabis use in patients with recent-onset psychosis and clinical high-risk for psychosis Nora Penzel,…, Stefan Borgwardt, … DOI: 10.1038/s41537-022-00218-y Abstract Continued cannabis use (CCu) is an important predictor for poor long-term outcomes in psychosis and clinically high-risk patients, but no generalizable model has hitherto been tested for its ability to …

Pattern of predictive features of continued cannabis use in patients with recent-onset psychosis and clinical high-risk for psychosis Read More »

The Basal Forebrain Cholinergic Nuclei and Their Relevance to Schizophrenia and Other Psychotic Disorders Sofia Eickhoff, Léon Franzen, Alexandra Korda, Helena Rogg, Valerie-Noelle Trulley, Stefan Borgwardt & Mihai Avram   DOI: 10.3389/fpsyt.2022.909961 Abstract The basal forebrain cholinergic nuclei (BFCN) provide the main cholinergic input to prefrontal cortices, the hippocampi, and amygdala. These structures are highly relevant for the regulation and maintenance of many …

The Basal Forebrain Cholinergic Nuclei and Their Relevance to Schizophrenia and Other Psychotic Disorders Read More »

Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia Felix Brandl, …Mihai Avram,… Brain, awac268doi: 10.1093/brain/awac268   Abstract Negative symptoms, such as lack of motivation or social withdrawal, are highly prevalent and debilitating in patients with schizophrenia. Underlying mechanisms of negative symptoms are incompletely understood, thereby preventing the development of targeted treatments. We hypothesized that …

Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia Read More »