Publications

The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis Frederike Schröpfer, Emilia Greif, Sofia Eickhoff, … , Stefan Borgwardt & Léon Franzen  DOI: 10.1007/s00787-025-02937-w Abstract Mental disorders represent a significant challenge for individuals and society. Many of them have […]

Perspectives of mothers and fathers affected by addiction of an adolescent/adult child – results from a mixed-method study Anja Bischof, Richard Velleman, Stefan Borgwardt, Hans-Juergen Rumpf & Gallus Bischof DOI: 10.1186/s13690-025-01826-7 Abstract Background Addiction has an impact not only on the individual but also on family members. Stress and strain are high especially in parents

Mapping symptom dimensions in early psychosis through neurotransmitter-informed co-localization of structural and functional brain alterations L. Hahn, M. Sacha, … , S Borgwardt, …  DOI: 10.1016/j.nsa.2025.106605 Abstract Traditional diagnostic tools like the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) and the Scale for the Assessment of Negative Symptoms (SANS) assess broad symptom domains but

Mental health, coping and related risk factors during the first 2 years of the COVID-19 pandemic in children: Nationally representative, multi-wave, cross-sectional results from 12 countries from the global COH-FIT study Agorastos Agorastos, Trevor Thompson, … , Stefan Borgwardt, … DOI: 10.1016/j.euroneuro.2025.112741 Abstract Few multinational studies have assessed risk factors and coping strategies associated with

Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis David Popovic, … , Stefan Borgwardt, Stephen J Wood, Eva Meisenzahl, Nikolaos Koutsouleris, Rachel Upthegrove, PRONIA Consortium  DOI: 10.1001/jamapsychiatry.2025.3803 Abstract Importance  Inflammation is increasingly implicated in the pathophysiology of mood and psychotic disorders. Integrating blood biomarkers and brain imaging may help uncover mechanistic pathways and guide targeted interventions.

Structural covariance network topology in individuals at clinical high risk for psychosis: the ENIGMA-CHR Study Siwei Liu, Ingrid Agartz, Paul Allen, G Paul Amminger, Ole A Andreassen, Peter Bachman, Inmaculada Baeza, Helen Baldwin, Cali F Bartholomeusz, Stefan Borgwardt, …  DOI: 10.1038/s41380-025-03304-6 Abstract Brain network architecture is anticipated to influence future grey matter loss in individuals

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Madalina-Octavia Buciuman, Shalaila S Haas, … , Stefan Borgwardt, Dominic B Dwyer, Lana Kambeitz-Ilankovic, Nikolaos Koutsouleris DOI:  10.1016/j.biopsych.2025.07.003 Abstract Background Early recovery of functioning is critical for favorable outcomes in psychotic and affective disorders.

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression Svenja Sürig, … ,  Stefan Borgwardt, Jan Philipp Klein, Thomas Probst DOI: 10.1080/16506073.2025.2464641   Abstract While most psychotherapy methods are about equally effective, it is unclear if (1) different methods of psychotherapy differ

Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia Zoey Stark, Karine Elalouf, Vanessa Soldano, Léon Franzen & Aaron P. Johnson DOI: 10.1002/dys.1797   Abstract Dyslexia is a language-based neurobiological and developmental learning disability marked by inaccurate and disfluent word recognition, poor decoding, and difficulty spelling. Individuals can be diagnosed with and

Individualized pretest risk estimates to guide treatment decisions inpatients with clinical high risk for psychotic disorders Elodie Sprüngli-Toffel,  … , Stefan Borgwardt, Christina Andreou DOI: 10.1016/j.sjpmh.2024.09.001   Abstract Introduction: Clinical high risk for psychosis (CHR) states are associated with an increased risk of transition to psychosis. However, the predictive value of CHR screening interviews is