Publications

Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia

Negative symptoms, striatal dopamine, and model-free reward decision-making in schizophrenia Felix Brandl, …Mihai Avram,… Brain, awac268doi: 10.1093/brain/awac268   Abstract Negative symptoms, such as lack of motivation or social withdrawal, are highly prevalent and debilitating in patients with schizophrenia. Underlying mechanisms of negative symptoms are incompletely understood, thereby preventing the development of targeted treatments. We hypothesized that …

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Latent state-trait structure of BPRS subscales in clinical high-risk state and first episode psychosis

  Latent state-trait structure of BPRS subscales in clinical high-risk state and first episode psychosis Hochstrasser, L., … S. Borgwardt …    Scientific Reports doi: 10.1038/s41598-022-10207-x   Abstract To investigate the longitudinal latent state-trait structure of the different dimensions of psychosis symptoms in clinical high-risk state (CHRS) and first episode psychosis (FEP) individuals over a one …

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Novel Gyrification Networks Reveal Links with Psychiatric Risk Factors in Early Illness

Novel Gyrification Networks Reveal Links with Psychiatric Risk Factors in Early Illness Sanfelici, R. … S. Borgwardt … PRONIA Consortium   2022. Cerebral Cortex doi: 10.1093/cercor/bhab288   Abstract Adult gyrification provides a window into coordinated early neurodevelopment when disruptions predispose individuals to psychiatric illness. We hypothesized that the echoes of such disruptions should be observed …

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Clinical, Brain, and Multilevel Clustering in Early Psychosis and Affective Stages

Clinical, Brain, and Multilevel Clustering in Early Psychosis and Affective Stages Dwyer, D. B. … C. Andreou … S. Borgwardt … PRONIA Consortium   2022. JAMA Psychiatry doi: 10.1001/jamapsychiatry.2022.1163   Abstract Importance: Approaches are needed to stratify individuals in early psychosis stages beyond positive symptom severity to investigate specificity related to affective and normative variation and …

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Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes

Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes Lalousis, P. A. … C. Andreou … S. Borgwardt    2022. Biological Psychiatry doi: 10.1016/j.biopsych.2022.03.021   Abstract Background Identifying neurobiologically based transdiagnostic categories of depression and psychosis may elucidate heterogeneity and provide better candidates for predictive modeling. We aimed to identify …

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The relationship between psychological characteristics of patients and their utilization of psychiatric inpatient treatment: A cross-sectional study, using machine learning

The relationship between psychological characteristics of patients and their utilization of psychiatric inpatient treatment: A cross-sectional study, using machine learning Lo, S. B. … S. Borgwardt, Lang, U. & Moeller, J.   2022. PLoS One. doi: 10.1371/journal.pone.0266352   Abstract High utilizers (HU) are patients with an above-average use of psychiatric inpatient treatment. A precise characterization …

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Special Issue “Psychosis: Clinical Management and Challenges” – call for submissions

  Special Issue “Psychosis: Clinical Management and Challenges” – call for submissions   We are pleased to invite submissions for special issue with the title “Psychosis: Clinical Management and Challenges” in the Journal of Clinical Medicine, an open access journal by MDPI (IF 4.242), edited by Prof. Christina Andreou in collaboration with Prof. Marco Armando …

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Increased Belief Instability in Psychotic Disorders Predicts Treatment Response to Metacognitive Training

Increased Belief Instability in Psychotic Disorders Predicts Treatment Response to Metacognitive Training D. J. Hauke, V. Roth, P. Karvelis, R. A. Adams, S. Moritz, S. Borgwardt, A. O. Diaconescu, & C. Andreou   2022. Schizophrenia Bulletin. doi: 10.1093/schbul/sbac029   Abstract Background and Hypothesis: In a complex world, gathering information and adjusting our beliefs about the world …

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Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants

Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants Müller, F. … S. Borgwardt   2022. Psychopharmacology. doi: 10.1007/s00213-022-06066-z   Abstract Background LSD and psilocybin are increasingly used in phase I trials and evaluated as therapeutic agents for mental dis-orders. The phenomenon of reoccurring drug-like experiences after the acute substance …

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Latent state-trait structure of BPRS subscales in clinical high-risk state and first episode psychosis

Latent state-trait structure of BPRS subscales in clinical high-risk state and first episode psychosis Hochstrasser, L. … S. Borgwardt …   2022. Scientific Reports. doi: 10.1038/s41598-022-10207-x   Abstract To investigate the longitudinal latent state-trait structure of the different dimensions of psychosis symptoms in clinical high-risk state (CHRS) and first episode psychosis (FEP) individuals over a …

Latent state-trait structure of BPRS subscales in clinical high-risk state and first episode psychosis Read More »

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