News

Klinische Routinedaten und innovative Therapieansätze – Implikationen für die Weiterentwicklung der Psychiatrie und Neuropsychiatrie Stefan Borgwardt DOI: 10.1055/a-2813-6755 Abstract Die aktuelle psychiatrisch und neuropsychiatrische Versorgung

Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis Xi Yang, Ingrid Agartz, Ole Andreassen, Peter Bachman, Inmaculada Baeza, Cali

Zusammenhänge von Veränderungen psychischer Flexibilität und Veränderungen psychischer Gesundheit: Eine Netzwerkanalyse Boris Jakov Entus, Nele Assmann, Catarina Newe, Eva Fassbinder, Hans Anton Huth, Stefan Borgwardt,

Biosignatures of cognitive basic symptoms mark a distinct neurodevelopmental pathway to schizophrenia Nikolaos Koutsouleris, Clara Vetter, … ,  Alexandra Korda, Alessandro Bertolino, Stefan Borgwardt, …

Evidence of phenotypes indexing cognitive resilience and vulnerability in the early course of mood and psychosis spectrum illness; mapping the latent structure, characteristics, and longitudinal

Task-aware multiple instance learning for stress detection from facial video data Nele Sophie Brügge, Alexandra Korda, Heinz Handels & Giorgos Giannakakis  DOI: 10.1016/j.jad.2026.121472 Abstract Stress

Brain texture alterations predict subtle visualperceptual dysfunctions in recent onset psychosisand clinical high-risk state Rebekka Lencer, … , Stefan Borgwardt, Christina Andreou, Alexandra Korda &

Mental health outcomes in young adolescents born preterm reveal the need for earlier screening Emilia Greif, Frederike Schröpfer, Jekaterina Dudko, …, Stefan Borgwardt & Léon

The Perception of Visual Distortions in Virtual Reality andTheir Association with Psychosis-Relevant Traits Fabian D. Mueller, … , Léon Franzen, …  DOI: 10.31234/osf.io/pfy6u_v2 Abstract Background

Psychedelics distinctly alter brain entropy and complexity compared to psychostimulants K. Larsen, … , S. Borgwardt, F. Holze, L. Ley, P. Vizeli, A. Klaiber, A.M.

Neural Dynamics of Social Cognition: A Single-TrialComputational Analysis of Learning Under Uncertainty Colleen E Charlton, Daniel J Hauke, … ,  Stefan Borgwardt, …  DOI: 10.1002/hbm.70433

The impact of premature birth and low birth weight on motor, visual, and cognitive skills and mental health in adolescence: a systematic review and meta-analysis

Perspectives of mothers and fathers affected by addiction of an adolescent/adult child – results from a mixed-method study Anja Bischof, Richard Velleman, Stefan Borgwardt, Hans-Juergen

Mapping symptom dimensions in early psychosis through neurotransmitter-informed co-localization of structural and functional brain alterations L. Hahn, M. Sacha, … , S Borgwardt, …  DOI:

Mental health, coping and related risk factors during the first 2 years of the COVID-19 pandemic in children: Nationally representative, multi-wave, cross-sectional results from 12

Multivariate Brain-Blood Signatures in Early-Stage Depression and Psychosis David Popovic, … , Stefan Borgwardt, Stephen J Wood, Eva Meisenzahl, Nikolaos Koutsouleris, Rachel Upthegrove, PRONIA Consortium 

Structural covariance network topology in individuals at clinical high risk for psychosis: the ENIGMA-CHR Study Siwei Liu, Ingrid Agartz, Paul Allen, G Paul Amminger, Ole

From Snapshots to Stable Outcomes: Resting-State Functional Magnetic Resonance Imaging–Based Prognosis of Functioning in Patients With Psychosis Risk or Recent-Onset Depression Madalina-Octavia Buciuman, Shalaila S

Negative effects of psychotherapy and their differential association with long-term outcome: an observational study of an intensive day treatment program for depression Svenja Sürig, …

Validation and Reliability of the Dyslexia Adult Checklist in Screening for Dyslexia Zoey Stark, Karine Elalouf, Vanessa Soldano, Léon Franzen & Aaron P. Johnson DOI:

Individualized pretest risk estimates to guide treatment decisions inpatients with clinical high risk for psychotic disorders Elodie Sprüngli-Toffel,  … , Stefan Borgwardt, Christina Andreou DOI:

Large-scale brain connectivity changes following the administration of lysergic acid diethylamide, d-amphetamine, and 3,4-methylenedioxyamphetamine Mihai Avram, …, Alexandra Korda, …, Helena Rogg, …, Stefan Borgwardt 

Serum Metabolites as Potential Markers and Predictors of Depression-like Behavior and Effective Fluoxetine Treatment in Chronically Socially Isolated Rats Dragana Filipović, … , Alexandra Korda,

We like to move it – patients with schizophrenia spectrum disorders are impaired in estimating their physical fitness levels and benefit from individualized exercise Wido Rippe,

Verbal Learning and Memory Deficits across Neurological and Neuropsychiatric Disorders: Insights from an ENIGMA Mega Analysis Eamonn Kennedy, …, Mihai Avram, …, Stefan Borgwardt, … DOI:

Which Are the Optimal Screening Tools for Internet Use Disorderin Children and Adolescents? A Systematic Review of PsychometricEvidence Samantha Schlossarek, …, Stefan Borgwardt, … DOI: 10.1007/s40429-024-00568-w

Neurobiologie und Wirkmodelle zu Psychedelika Neurobiology and modes of action of psychedelics Uwe Herwig, Mihai Avram, Stefan Borgwardt, … DOI: 10.1055/a-2261-0745 Zusammenfassung Zur Beantwortung der Frage,

Evidence from comprehensive independent validation studies for smooth pursuit dysfunction as a sensorimotor biomarker for psychosis Inga Meyhoefer, … Stefan Borgwardt, … DOI: 10.1038/s41598-024-64487-6 Abstract Smooth

Anhedonia as a potential transdiagnostic phenotype with immune-related changes in recent onset mental health disorders Paris Alexandros Lalousis, … Stefan Borgwardt, … DOI: 10.1016/j.biopsych.2024.05.019 Abstract Background Chronic

Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study Marco Solmi, … Stefan Borgwardt, … DOI:

Distinct Volume Alterations of Thalamic Nuclei Across the Schizophrenia Spectrum Melissa Thalhammer, … Stefan Borgwardt, … Mihai Avram,…  DOI: doi.org/10.1093/schbul/sbae037 Abstract Background and Hypothesis Abnormal thalamic

Für ein besseres Verständnis anhaltender Wahrnehmungsstörungen nach der Einnahme klassischer Psychedelika Towards a Better understanding of Persisting Perceptual Disturbances following the use of Classic Psychedelics.

Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system – a retrospective cohort study Katharina Wien,

Clinical and histopathological characteristics of acute kidney injury in a cohort of brain death donors with procurement biopsies Florian G. Scurt, …, Alexandra Korda, …

Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders Linnea Hoheisel, … Stefan Borgwardt, … PRONIA Consortium   DOI: 10.1016/j.bpsc.2024.02.013 Abstract Background Psychosis and depression patients exhibit

  Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning Else Schneider, … Stefan Borgwardt, …  DOI: 10.3389/fnagi.2024.1357695 Summary Associative

Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation Ruiyang Ge, … Stefan Borgwardt, …   DOI: 10.1016/S2589-7500(23)00250-9 Summary The

Altered Perception of Environmental Volatility During Social Learning in Emerging Psychosis Daniel J. Hauke, … Christina Andreou, … Stefan Borgwardt, …  DOI: 10.5334/cpsy.95 Abstract Paranoid

Management of treatment resistance-Treatment-resistant schizophrenia Elias Wagner, Stefan Borgwardt & Alkomiet Hasan      DOI: 10.1007/s00115-024-01608-6 Abstract Despite a very high prevalence and substantial impairments among

In a recent radio interview with the Offener Kanal Lübeck (Open Channel Lübeck) Marco Heide, the medical head of our Baltic Early Treatment Service (BEATS), elaborated

Brain texture as a marker of transdiagnostic clinical profiles in patients with recent-onset psychosis and depression Alexandra Korda, Christina Andreou … Stefan Borgwardt & the

Back to the Future: On the Road Towards Precision Psychiatry, Volume II Paul Guest, Stefan Borgwardt & Johann Steiner   DOI: 10.3389/fpsyt.2023.1355085 Abstract However, in

Normative tDCS over V5 and FEF reveals practice-induced modulation of extraretinal smooth pursuit mechanisms, but no specific stimulation effect Jan-Ole Radecke, … Stefan Borgwardt, … 

Basal-Forebrain Cholinergic Nuclei Alterations are Associated With Medication and Cognitive Deficits Across the Schizophrenia Spectrum Julia Schulz, … Stefan Borgwardt … & Mihai Avram   DOI: 10.1093/schbul/sbad118

Effective-connectivity of thalamocortical interactions following d-amphetamine, LSD, and MDMA administration Mihai Avram … Helena Rogg, Alexandra Korda … & Stefan Borgwardt 2023, Biological Psychiatry DOI:

In a recent radio interview with the NDR Stefan Borgwardt highlighted the wide-ranging support the Baltic Early Treatment Service (BEATS) Lübeck offers to help-seeking adolescents

A recent article in The Zeit explores the evidence for the serotonin hypothesis of depression including an interview with Stefan Borgwardt. Specifically, it critically examines

The non-specific nature of mental health and structural brain outcomes following childhood trauma Theresa K Haidl, …. Stefan Borgwardt  2023, Psychol Med DOI: 10.1017/S0033291721002439 Abstract

Chaos analysis of the cortical boundary for the recognition of psychosis Alexandra I. Korda, Christina Andreou, Mihai Avram, Marina Frisman, …, Stefan Borgwardt  2023, J

Circadian rhythms in auditory hallucinations and psychosis Hong-Viet V Ngo, … Christina Andreou, …  2023, Acta Physiol DOI: 10.1111/apha.13944 Abstract Circadian rhythms are imprinted in

Lysergic acid diethylamide: In search of the wonder drug  Mihai Avram, Felix Müller, Stefan Borgwardt  2023, Book: Psychedelics as psychiatric medications Link to the chapter

Effects of a probiotic add-on treatment on fronto-limbic brain structure, function, and perfusion in depression: Secondary neuroimaging findings of a randomized controlled trial  Gulnara Yamanbaeva,

Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trial  Yu-Shiuan Lin, … Stefan Borgwardt, …. 

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a randomized controlled trial

How to Run Behavioural Experiments Online: Best Practice Suggestions for Cognitive Psychology and Neuroscience Nathan Gagné and Léon Franzen  2023, Swiss Psychology Open: The Official

Psychedelics in Psychiatry – Development and Current State in Germany Uwe Herwig, …, Stefan Borgwardt, …  2023, Fortschritte der Neurologie-Psychiatrie DOI: 10.1055/a-1981-3152

Ketamine as a Treatment Option for Severe Borderline Personality Disorder: A Case Report Helena Rogg, Mihai Avram, …, Stefan Borgwardt, …  2023, Journal of Clinical

Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium Constantinos Constantinides, …, Stefan Borgwardt, …  2022, medRxiv – Psychiatry and

Relationships between global functioning and neuropsychological predictors in subjects at high risk of psychosis or with a recent onset of depression Letizia Squarcina, … Stefan

Attitudes of Medical Students Towards Alcohol-Related Disorders: Dependent on Intended Medical Specialization? Hannah Schmidt, …. Stefan Borgwardt, … 2022, Psychiatr Prax  DOI: 10.1055/a-1690-5902 Abstract The

Identification of texture MRI brain abnormalities on first-episode psychosis and clinical high-risk subjects using explainable artificial intelligence Alexandra I. Korda , Christina Andreou , Helena

Evidence of discontinuity between psychosis-risk and non-clinical samples in the neuroanatomical correlates of social function Shalaila S. Haas, … Stefan Borgwardt, …. 2022, Schizophrenia Research

Study protocol for a randomised controlled trial of an e-health stepped care approach for the treatment of internet use disorders versus a placebo condition: the

Chaos analysis of the brain topology in first-episode psychosis and clinical high risk patients Alexandra Korda, Christina Andreou, Mihai Avram, … Stefan Borgwardt 2022, Frontiers

The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis Johanna M. Schwarzer, … Alexandra Korda, … Stefan Borgwardt … 2022, Neuropsychopharmacology DOI:

Motivational brief interventions for adolescents and young adults with Internet use disorders: A randomized-controlled trial Hannah Schmidt, … Stefan Borgwardt  2022, Journal of Behavioral Addictions DOI: 10.1556/2006.2022.00049

Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes Paris Alexandros Lalousis, … Christina Andreou  2022, Biological Psychiatry DOI: doi.org/10.1016/j.biopsych.2022.03.021 Abstract Identifying neurobiologically based

Influence of chronotype on the incidence and severity of perinatal depression in the “Life-ON” study Corrado Garbazza, …. Stefan Borgwardt,… 2022, Journal of Affective Disorders DOI: 10.1016/j.jad.2022.08.064

The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis Johanna M Schwarzer … Alexandra Korda … Stefan Borgwardt  2022, Neuropsychopharmacology DOI:

Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited Nikolaos Koutsouleris, … Stefan Borgwardt, ….  DOI: 10.1001/jamapsychiatry.2022.2075 Abstract The behavioral and

  Special Collection on  “Hallucinations and Delusions” – call for submissions   Hallucination is understood as the perception of something that is not there and

Think-aloud analysis of commonly used screening instruments for Internet use disorders: The CIUS, the IGDT-10, and the BSMAS Hannah Schmidt, … Stefan Borgwardt, ….  DOI: 10.1556/2006.2022.00034

Pattern of predictive features of continued cannabis use in patients with recent-onset psychosis and clinical high-risk for psychosis Nora Penzel,…, Stefan Borgwardt, … DOI: 10.1038/s41537-022-00218-y Abstract